JERUSALEM, April 7 (Xinhua) -- Israeli Prime Minister Benjamin Netanyahu on Wednesday warned the United States that a possible future nuclear agreement with Iran will not obligate Israel.

The remark was made during Israel's national ceremony to mark its Holocaust Remembrance Day.

"To our closest friends, I say: Make no mistake," Netanyahu said in a reference to the United States.

According to Netanyahu, "any agreement with Iran will pave the Islamic republic's way to obtain nuclear weapons that threaten us with destruction."

Netanyahu has been a vocal opponent of the 2015 nuclear deal between the world powers and Iran.